Grants Roundup: College of Engineering Receives $1.7 Million in Grants in Q2
棉花糖直播 University鈥檚 College of Engineering added $1.7 million in anticipated grant funding to its portfolio in the second quarter of 2022-2023, bringing the total award amount to nearly $7 million for the fiscal year. The awards, provided by the National Institutes of Health and the National Science Foundation, will support three projects led by members of the 棉花糖直播 Engineering faculty.
Meltem Izzetoglu, PhD
Electrical and Computer Engineering
National Institutes of Health: $1,171,812
Collaborative Research: SCH: Early Assessment of Cognitive Decline using Multimodal Neuroimaging with Embedded Artificial Intelligence
In this project, we will develop an integrated platform for the assessment of mild cognitive impairments (MCI) in older adults using multimodal neuroimaging information obtained from functional near infrared spectroscopy (fNIRS) and electroencephalography (EEG) with advanced signal processing and data science methods including cutting-edge Artificial Intelligence/Machine Learning (AI/ML) techniques. Developing a mobile application that combines a comprehensive cognitive testing battery sensitive to MCI together with fNIRS-EEG on one platform that could be used in less expensive and restrictive testing environments to determine functional brain alterations in older adults with MCI is very innovative. The findings of this project can lead to a transformation in early detection and monitoring of cognitive decline in older adults at risk of developing Alzheimer's disease.聽
Laura Bracaglia, PhD
Chemical and Biological Engineering
National Institutes of Health: $742,050 (total anticipated funding)
Tailored siRNA delivery to human endothelium to inhibit and reverse inflammatory damage following ischemia reperfusion injury in the kidney
Ischemia reperfusion injury (IRI) causes endothelial inflammation and microvascular rarefaction that leads to adverse kidney graft outcomes in organ transplant. Direct treatment of endothelial cells (EC) can reduce the impact of IRI on the health of the graft, but there is a lack of EC targeted therapies that can effectively intervene and alleviate the various modes of dysfunctional endothelial response. The goal of this work is to develop a therapeutic strategy that addresses the two key modes of endothelial damage in response to IRI: dysfunctional inflammation in ECs and damage to capillary networks, in a site-specific and temporary manner.
Alfonso Ortega, PhD
Center for Energy-Smart Electronic Systems (ES2)
National Science Foundation: $50,000
Industry/University Cooperative Research Center for Energy Smart Electronic Systems: Phase III
Dr. Ortega鈥檚 most recent grant supports research conducted within the Center for Energy-Smart Electronic Systems, a National Science Foundation Industry/University Cooperative Research Center (I/UCRC) established to develop methodologies, tools and systems that will maximize energy efficiency for the operation of electronic systems, including data centers, 鈥渇rom the chip to the cooling tower.鈥�